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Donor Semen Insemination (also called Therapeutic Donor Insemination – TDI) is a modern fertility treatment where donor sperm is used to help individuals or couples achieve pregnancy. This can be done through IUI (Intrauterine Insemination) or IVF (In Vitro Fertilization). It is ideal for cases of male infertility, genetic concerns, or when no male partner is involved.
Who Can Benefit?
This program is suitable for:
Men with severe male infertility (low sperm count, poor motility, or azoospermia)
Men carrying genetic conditions they do not wish to pass on
Single women or women in same-sex relationship
Men with ejaculatory problems or other medical issues affecting sperm
Couples with previous failed ICSI or IVF cycles due to poor sperm quality
How the Donor Semen Process Works
Donors are healthy men aged 21-55
Complete medical, genetic, and infectious disease screening is performed
Recipients can choose an anonymous or known donor based on traits, ethnicity, and medical history
Donor sperm is collected, processed, and cryopreserved
A 6-month quarantine ensures safety and rules out infectious diseases
IUI: Processed donor sperm is inserted directly into the uterus during ovulation
IVF: Donor sperm fertilizes eggs in the lab, and embryos are transferred to the uterus
A blood test (Beta hCG) is done 10–14 days after insemination
If positive, the pregnancy is monitored like a natural one with regular checkups
Success Rates
IUI with donor sperm: 15–25% per cycle, increasing with multiple attempts
IVF with donor sperm: 50–70% per cycle, depending on egg quality
Benefits of Donor Semen Insemination
✅ Simple & Non-Invasive: IUI is quick, safe, and nearly painless
✅ Higher Pregnancy Success: Particularly for severe male infertility cases
✅ Healthy & Screened Sperm: Donors undergo thorough medical and genetic testing
✅ Flexible Treatment: Donor sperm can also be used in IVF or ICSI
✅ Safe & Regulated: Legal and ethical guidelines ensure safety for both parents and child
Emotional & Legal Considerations
Counseling is recommended to address emotional aspects
Some may find it challenging that there is no genetic link from the male partner
Legal rules regarding donor anonymity and parental rights vary by country
Conclusion
Donor Semen Insemination provides a safe and effective route to parenthood for individuals and couples facing male infertility or genetic concerns. At Manasi Clinic, we offer personalized donor sperm programs with strict screening, ethical practices, and compassionate guidance to help you achieve your dream of having a child.